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Correlation of disease severity with body weight and high fat diet in the FATZO/Pco mouse

Obesity in many current pre-clinical animal models of obesity and diabetes is mediated by monogenic mutations; these are rarely associated with the development of human obesity. A new mouse model, the FATZO mouse, has been developed to provide polygenic obesity and a metabolic pattern of hyperglycem...

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Detalles Bibliográficos
Autores principales: Droz, Brian A., Sneed, Bria L., Jackson, Charles V., Zimmerman, Karen M., Michael, M. Dodson, Emmerson, Paul J., Coskun, Tamer, Peterson, Richard G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5480996/
https://www.ncbi.nlm.nih.gov/pubmed/28640904
http://dx.doi.org/10.1371/journal.pone.0179808