Epidermal growth factor promotes cyclin G2 degradation via calpain-mediated proteolysis in gynaecological cancer cells

Cyclin G2 (CCNG2) is an atypical cyclin that functions to inhibit cell cycle progression and is often dysregulated in human cancers. We have previously shown that cyclin G2 is highly unstable and can be degraded through the ubiquitin/proteasome pathway. Furthermore, cyclin G2 contains a PEST domain,...

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Detalles Bibliográficos
Autores principales: Bernaudo, Stefanie, Khazai, Shahin, Honarparvar, Eilyad, Kopteva, Alina, Peng, Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481008/
https://www.ncbi.nlm.nih.gov/pubmed/28640887
http://dx.doi.org/10.1371/journal.pone.0179906

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481008/
https://www.ncbi.nlm.nih.gov/pubmed/28640887
http://dx.doi.org/10.1371/journal.pone.0179906

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