Cargando…

Epidermal growth factor promotes cyclin G2 degradation via calpain-mediated proteolysis in gynaecological cancer cells

Cyclin G2 (CCNG2) is an atypical cyclin that functions to inhibit cell cycle progression and is often dysregulated in human cancers. We have previously shown that cyclin G2 is highly unstable and can be degraded through the ubiquitin/proteasome pathway. Furthermore, cyclin G2 contains a PEST domain,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Bernaudo, Stefanie, Khazai, Shahin, Honarparvar, Eilyad, Kopteva, Alina, Peng, Chun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481008/ https://www.ncbi.nlm.nih.gov/pubmed/28640887 http://dx.doi.org/10.1371/journal.pone.0179906

Ejemplares similares

miR-590-3p Targets Cyclin G2 and FOXO3 to Promote Ovarian Cancer Cell Proliferation, Invasion, and Spheroid Formation
por: Salem, Mohamed, et al.
Publicado: (2019)

Calpain-mediated proteolysis as driver and modulator of polyglutamine toxicity
por: Incebacak Eltemur, Rana Dilara, et al.
Publicado: (2022)

The Growth and Tumor Suppressors NORE1A and RASSF1A Are Targets for Calpain-Mediated Proteolysis
por: Kuznetsov, Sergey, et al.
Publicado: (2008)

Dual vulnerability of tau to calpains and caspase-3 proteolysis under neurotoxic and neurodegenerative conditions
por: Cheng Liu, Ming, et al.
Publicado: (2011)

Calpain A modulates Toll responses by limited Cactus/IκB proteolysis
por: Fontenele, Marcio, et al.
Publicado: (2013)

Calpain-10 regulates actin dynamics by proteolysis of microtubule-associated protein 1B
por: Hatta, Tomohisa, et al.
Publicado: (2018)

Inhibiting calpain 1 and 2 in cyclin G associated kinase–knockout mice mitigates podocyte injury
por: Tian, Xuefei, et al.
Publicado: (2020)

Ip-10 Inhibits Epidermal Growth Factor–Induced Motility by Decreasing Epidermal Growth Factor Receptor–Mediated Calpain Activity
por: Shiraha, Hidenori, et al.
Publicado: (1999)

Calpain-Catalyzed Proteolysis of Human dUTPase Specifically Removes the Nuclear Localization Signal Peptide
por: Bozóky, Zoltán, et al.
Publicado: (2011)

Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle
por: Gokhin, David S., et al.
Publicado: (2014)

l‐arginine ingestion inhibits eccentric contraction‐induced proteolysis and force deficit via S‐nitrosylation of calpain
por: Kanzaki, Keita, et al.
Publicado: (2018)

Calpain-mediated proteolysis of vimentin filaments is augmented in giant axonal neuropathy fibroblasts exposed to hypotonic stress
por: Phillips, Cassandra L., et al.
Publicado: (2022)

Fam20c regulates the calpain proteolysis system through phosphorylating Calpasatatin to maintain cell homeostasis
por: Liu, Xinpeng, et al.
Publicado: (2023)

Impact of polymorphism of the regulatory subunit of the μ-calpain (CAPN1S) on the proteolysis process and meat tenderness of young cattle
por: Iwanowska, Agnieszka, et al.
Publicado: (2010)

Propofol Ameliorates Calpain-induced Collapsin Response Mediator Protein-2 Proteolysis in Traumatic Brain Injury in Rats
por: Yu, Yun, et al.
Publicado: (2015)

Cyclin G2 inhibits epithelial-to-mesenchymal transition by disrupting Wnt/β-catenin signaling
por: Bernaudo, S, et al.
Publicado: (2016)

Ordered dephosphorylation initiated by the selective proteolysis of cyclin B drives mitotic exit
por: Holder, James, et al.
Publicado: (2020)

Erratum: Cyclin G2 inhibits epithelial-to-mesenchymal transition by disrupting Wnt/β-catenin signalling
por: Bernaudo, S, et al.
Publicado: (2016)

Proteasome- and Calpain-Mediated Proteolysis, but Not Autophagy, Is Required for Leucine-Induced Protein Synthesis in C2C12 Myotubes
por: Osburn, Shelby C., et al.
Publicado: (2021)

Calpain-Mediated Degradation of Drebrin by Excitotoxicity In vitro and In vivo
por: Chimura, Takahiko, et al.
Publicado: (2015)

Perturbation with Intrabodies Reveals That Calpain Cleavage Is Required for Degradation of Huntingtin Exon 1
por: Southwell, Amber L., et al.
Publicado: (2011)

Calpains in cyanobacteria and the origin of calpains
por: Vešelényiová, Dominika, et al.
Publicado: (2022)

Histone proteolysis: A proposal for categorization into ‘clipping’ and ‘degradation’
por: Dhaenens, Maarten, et al.
Publicado: (2015)

Assays and technologies for developing proteolysis targeting chimera degraders
por: Liu, Xingui, et al.
Publicado: (2020)

Calpain 8/nCL-2 and Calpain 9/nCL-4 Constitute an Active Protease Complex, G-Calpain, Involved in Gastric Mucosal Defense
por: Hata, Shoji, et al.
Publicado: (2010)

Proteolysis of the Human DNA Polymerase Delta Smallest Subunit p12 by μ-Calpain in Calcium-Triggered Apoptotic HeLa Cells
por: Fan, Xiaoting, et al.
Publicado: (2014)

Monophosphorylation of cardiac troponin-I at Ser-23/24 is sufficient to regulate cardiac myofibrillar Ca(2+) sensitivity and calpain-induced proteolysis
por: Martin-Garrido, Abel, et al.
Publicado: (2018)

E2F1 proteolysis via SCF‐cyclin F underlies synthetic lethality between cyclin F loss and Chk1 inhibition
por: Burdova, Kamila, et al.
Publicado: (2019)

Predictions of Cleavability of Calpain Proteolysis by Quantitative Structure-Activity Relationship Analysis Using Newly Determined Cleavage Sites and Catalytic Efficiencies of an Oligopeptide Array
por: Shinkai-Ouchi, Fumiko, et al.
Publicado: (2016)

Protein Degradation by In-Cell Self-Assembly of Proteolysis Targeting Chimeras
por: Lebraud, Honorine, et al.
Publicado: (2016)

Differential Effects of Polyphenols on Insulin Proteolysis by the Insulin-Degrading Enzyme
por: Zheng, Qiuchen, et al.
Publicado: (2021)

Lenalidomide derivatives and proteolysis-targeting chimeras for controlling neosubstrate degradation
por: Yamanaka, Satoshi, et al.
Publicado: (2023)

Calpain-2 participates in the process of calpain-1 inactivation
por: Shinkai-Ouchi, Fumiko, et al.
Publicado: (2020)

Constitutive degradation of IκBα in human T lymphocytes is mediated by calpain
por: Ponnappan, Subramaniam, et al.
Publicado: (2005)

Prevention of calpain-dependent degradation of STK38 by MEKK2-mediated phosphorylation
por: Enomoto, Atsushi, et al.
Publicado: (2019)

Bacterial calpains and the evolution of the calpain (C2) family of peptidases
por: Rawlings, Neil D.
Publicado: (2015)

Novel calpain families and novel mechanisms for calpain regulation in Aplysia
por: Hastings, Margaret H., et al.
Publicado: (2017)

Commentary on: Calpain-2 participates in the process of calpain-1 inactivation
por: Kumari, Raniki, et al.
Publicado: (2021)

Proteolysis-targeting chimera (PROTAC) for targeted protein degradation and cancer therapy
por: Li, Xin, et al.
Publicado: (2020)

Disordered region of cereblon is required for efficient degradation by proteolysis-targeting chimera
por: Kim, Kidae, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_4tlf40cjoeftf2rurstl3mg4ms