MeCP2 regulates Tet1-catalyzed demethylation, CTCF binding, and learning-dependent alternative splicing of the BDNF gene in Turtle

MECP2 mutations underlying Rett syndrome cause widespread misregulation of gene expression. Functions for MeCP2 other than transcriptional are not well understood. In an ex vivo brain preparation from the pond turtle Trachemys scripta elegans, an intraexonic splicing event in the brain-derived neuro...

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Detalles Bibliográficos
Autores principales: Zheng, Zhaoqing, Ambigapathy, Ganesh, Keifer, Joyce
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481183/
https://www.ncbi.nlm.nih.gov/pubmed/28594324
http://dx.doi.org/10.7554/eLife.25384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481183/
https://www.ncbi.nlm.nih.gov/pubmed/28594324
http://dx.doi.org/10.7554/eLife.25384

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