A bend, flip and trap mechanism for transposon integration

Cut-and-paste DNA transposons of the mariner/Tc1 family are useful tools for genome engineering and are inserted specifically at TA target sites. A crystal structure of the mariner transposase Mos1 (derived from Drosophila mauritiana), in complex with transposon ends covalently joined to target DNA,...

Descripción completa

Detalles Bibliográficos
Autores principales: Morris, Elizabeth R, Grey, Heather, McKenzie, Grant, Jones, Anita C, Richardson, Julia M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Biophysics and Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481204/
https://www.ncbi.nlm.nih.gov/pubmed/27223327
http://dx.doi.org/10.7554/eLife.15537

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481204/
https://www.ncbi.nlm.nih.gov/pubmed/27223327
http://dx.doi.org/10.7554/eLife.15537

Ejemplares similares