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A bend, flip and trap mechanism for transposon integration

Cut-and-paste DNA transposons of the mariner/Tc1 family are useful tools for genome engineering and are inserted specifically at TA target sites. A crystal structure of the mariner transposase Mos1 (derived from Drosophila mauritiana), in complex with transposon ends covalently joined to target DNA,...

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Detalles Bibliográficos
Autores principales:	Morris, Elizabeth R, Grey, Heather, McKenzie, Grant, Jones, Anita C, Richardson, Julia M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2016
Materias:	Biophysics and Structural Biology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481204/ https://www.ncbi.nlm.nih.gov/pubmed/27223327 http://dx.doi.org/10.7554/eLife.15537

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