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Whole Exome Sequencing to Identify Genetic Variants Associated with Raised Atherosclerotic Lesions in Young Persons

We investigated the influence of genetic variants on atherosclerosis using whole exome sequencing in cases and controls from the autopsy study “Pathobiological Determinants of Atherosclerosis in Youth (PDAY)”. We identified a PDAY case group with the highest total amounts of raised lesions (n = 359)...

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Detalles Bibliográficos
Autores principales: Hixson, James E., Jun, Goo, Shimmin, Lawrence C., Wang, Yizhi, Yu, Guoqiang, Mao, Chunhong, Warren, Andrew S., Howard, Timothy D., Heide, Richard S. Vander, Van Eyk, Jennifer, Wang, Yue, Herrington, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481334/
https://www.ncbi.nlm.nih.gov/pubmed/28642624
http://dx.doi.org/10.1038/s41598-017-04433-x