Prevention of long-term memory loss after retrieval by an endogenous CaMKII inhibitor

CaMK2N1 and CaMK2N2 are endogenous inhibitors of calcium/calmodulin-dependent protein kinase II (CaMKII), a key synaptic signaling molecule for learning and memory. Here, we investigated the learning and memory function of CaMK2N1 by knocking-down its expression in dorsal hippocampus of mice. We fou...

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Detalles Bibliográficos
Autores principales: Vigil, Fabio Antonio, Mizuno, Keiko, Lucchesi, Walter, Valls-Comamala, Victoria, Giese, Karl Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481336/
https://www.ncbi.nlm.nih.gov/pubmed/28642476
http://dx.doi.org/10.1038/s41598-017-04355-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481336/
https://www.ncbi.nlm.nih.gov/pubmed/28642476
http://dx.doi.org/10.1038/s41598-017-04355-8

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