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Optimization of Variable Ventilation for Physiology, Immune Response and Surfactant Enhancement in Preterm Lambs
Preterm infants often require mechanical ventilation due to lung immaturity including reduced or abnormal surfactant. Since cyclic stretch with cycle-by-cycle variability is known to augment surfactant release by epithelial cells, we hypothesized that such in vivo mechanotransduction improves surfac...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481362/ https://www.ncbi.nlm.nih.gov/pubmed/28690548 http://dx.doi.org/10.3389/fphys.2017.00425 |