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Optimization of Variable Ventilation for Physiology, Immune Response and Surfactant Enhancement in Preterm Lambs

Preterm infants often require mechanical ventilation due to lung immaturity including reduced or abnormal surfactant. Since cyclic stretch with cycle-by-cycle variability is known to augment surfactant release by epithelial cells, we hypothesized that such in vivo mechanotransduction improves surfac...

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Detalles Bibliográficos
Autores principales: Bartolák-Suki, Erzsébet, Noble, Peter B., Bou Jawde, Samer, Pillow, Jane J., Suki, Béla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481362/
https://www.ncbi.nlm.nih.gov/pubmed/28690548
http://dx.doi.org/10.3389/fphys.2017.00425