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The Significance of the Sulfatase Pathway for Local Estrogen Formation in Endometrial Cancer

Endometrial cancer (EC) is the most common estrogen-dependent gynecological malignancy in the developed World. To investigate the local formation of estradiol (E2), we first measured the concentrations of the steroid precursor androstenedione (A-dione) and the most potent estrogen, E2, and we evalua...

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Detalles Bibliográficos
Autores principales: Sinreih, Maša, Knific, Tamara, Anko, Maja, Hevir, Neli, Vouk, Katja, Jerin, Aleš, Frković Grazio, Snježana, Rižner, Tea Lanišnik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481366/
https://www.ncbi.nlm.nih.gov/pubmed/28690541
http://dx.doi.org/10.3389/fphar.2017.00368