Systematic comparison of two whole-genome amplification methods for targeted next-generation sequencing using frozen and FFPE normal and cancer tissues

Sequencing key cancer-driver genes using formalin-fixed, paraffin-embedded (FFPE) cancer tissues is becoming the standard for identifying the best treatment regimen. However, about 25% of all samples are rejected for genetic analyses for reasons that include too little tissue to extract enough high...

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Detalles Bibliográficos
Autores principales: Mendez, Pedro, Fang, Li Tai, Jablons, David M., Kim, Il-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481435/
https://www.ncbi.nlm.nih.gov/pubmed/28642587
http://dx.doi.org/10.1038/s41598-017-04419-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481435/
https://www.ncbi.nlm.nih.gov/pubmed/28642587
http://dx.doi.org/10.1038/s41598-017-04419-9

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