High-throughput Screening of Small Molecule Inhibitors of the Streptococcus Quorum-sensing Signal Pathway

The main components of the quorum-sensing system are expected to be favorable targets for drug development to combat various chronic infectious diseases. ComA of Streptococcus is an ATP-binding cassette transporter containing a peptidase domain (PEP), which is essential for the quorum-sensing signal...

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Detalles Bibliográficos
Autores principales: Ishii, Seiji, Fukui, Kenji, Yokoshima, Satoshi, Kumagai, Kazuo, Beniyama, Youko, Kodama, Tetsuya, Fukuyama, Tohru, Okabe, Takayoshi, Nagano, Tetsuo, Kojima, Hirotatsu, Yano, Takato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481443/
https://www.ncbi.nlm.nih.gov/pubmed/28642545
http://dx.doi.org/10.1038/s41598-017-03567-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481443/
https://www.ncbi.nlm.nih.gov/pubmed/28642545
http://dx.doi.org/10.1038/s41598-017-03567-2

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