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Pharmacokinetic and pharmacodynamic modeling of cyadox against Clostridium perfringens in swine

The purpose of this study was to evaluate the activity of cyadox against Clostridium perfringens in swine and optimize the dosage regimen using ex vivo pharmacokinetic-pharmacodynamic (PK-PD) modeling. After oral administration, the ileum fluid of pigs containing the free cyadox was collected by imp...

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Detalles Bibliográficos
Autores principales: Yan, Lei, Xie, Shuyu, Chen, Dongmei, Pan, Yuanhu, Tao, Yanfei, Qu, Wei, Liu, ZhenLi, Yuan, Zonghui, Huang, Lingli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481453/
https://www.ncbi.nlm.nih.gov/pubmed/28642571
http://dx.doi.org/10.1038/s41598-017-03970-9