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RARRES2 functions as a tumor suppressor by promoting β-catenin phosphorylation/degradation and inhibiting p38 phosphorylation in adrenocortical carcinoma

Tumor suppressor genes and the immune system are critical players in inhibiting cancer initiation and/or progression. However, little is known about whether a tumor suppressor gene can function through both immune-dependent and -independent mechanisms. Retinoic acid receptor responder 2 (RARRES2) is...

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Detalles Bibliográficos
Autores principales: Liu-Chittenden, Yi, Jain, Meenu, Gaskins, Kelli, Wang, Sophie, Merino, Maria J., Kotian, Shweta, Gara, Sudheer Kumar, Davis, Sean, Zhang, Lisa, Kebebew, Electron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481486/
https://www.ncbi.nlm.nih.gov/pubmed/28114280
http://dx.doi.org/10.1038/onc.2016.497