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An amphipathic α-helix directs palmitoylation of the large intracellular loop of the sodium/calcium exchanger

The electrogenic sodium/calcium exchanger (NCX) mediates bidirectional calcium transport controlled by the transmembrane sodium gradient. NCX inactivation occurs in the absence of phosphatidylinositol 4,5-bisphosphate and is facilitated by palmitoylation of a single cysteine at position 739 within t...

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Detalles Bibliográficos
Autores principales: Plain, Fiona, Congreve, Samitha Dilini, Yee, Rachel Sue Zhen, Kennedy, Jennifer, Howie, Jacqueline, Kuo, Chien-Wen, Fraser, Niall J., Fuller, William
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481580/
https://www.ncbi.nlm.nih.gov/pubmed/28432123
http://dx.doi.org/10.1074/jbc.M116.773945