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Tim-3 and PD-1 regulate CD8(+) T cell function to maintain early pregnancy in mice

During pregnancy, CD8(+) T cells are important regulators in the balance of fetal tolerance and antiviral immunity. T-cell immunoglobulin mucin-3 (Tim-3) and programmed cell death-1 (PD-1) are well-recognized negative co-stimulatory molecules involved in viral persistence and tumor metastasis. Here,...

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Detalles Bibliográficos
Autores principales: XU, Yuan-Yuan, WANG, Song-Cun, LIN, Yi-Kong, LI, Da-Jin, DU, Mei-Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Society for Reproduction and Development 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481631/
https://www.ncbi.nlm.nih.gov/pubmed/28331165
http://dx.doi.org/10.1262/jrd.2016-177