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Tim-3 and PD-1 regulate CD8(+) T cell function to maintain early pregnancy in mice
During pregnancy, CD8(+) T cells are important regulators in the balance of fetal tolerance and antiviral immunity. T-cell immunoglobulin mucin-3 (Tim-3) and programmed cell death-1 (PD-1) are well-recognized negative co-stimulatory molecules involved in viral persistence and tumor metastasis. Here,...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Society for Reproduction and Development
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481631/ https://www.ncbi.nlm.nih.gov/pubmed/28331165 http://dx.doi.org/10.1262/jrd.2016-177 |