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Screening of Stat3 inhibitory effects of Korean herbal medicines in the A549 human lung cancer cell line

BACKGROUND: The transcription factor signal transducer and activator of transcription 3 (Stat3) is constitutively activated in many human cancers. It promotes tumor cell proliferation, inhibits apoptosis, induces angiogenesis and metastasis, and suppresses antitumor host immune responses. Therefore,...

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Detalles Bibliográficos
Autores principales: Park, Jong-Shik, Bang, Ok-Sun, Kim, Jinhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481713/
https://www.ncbi.nlm.nih.gov/pubmed/28664080
http://dx.doi.org/10.1016/j.imr.2013.10.004