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Cryptic indole hydroxylation by a non-canonical terpenoid cyclase parallels bacterial xenobiotic detoxification
Terpenoid natural products comprise a wide range of molecular architectures that typically result from C–C bond formations catalysed by classical type I/II terpene cyclases. However, the molecular diversity of biologically active terpenoids is substantially increased by fully unrelated, non-canonica...
Autores principales: | Kugel, Susann, Baunach, Martin, Baer, Philipp, Ishida-Ito, Mie, Sundaram, Srividhya, Xu, Zhongli, Groll, Michael, Hertweck, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481743/ https://www.ncbi.nlm.nih.gov/pubmed/28643772 http://dx.doi.org/10.1038/ncomms15804 |
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