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Francisella requires dynamic type VI secretion system and ClpB to deliver effectors for phagosomal escape

Francisella tularensis is an intracellular pathogen that causes the fatal zoonotic disease tularaemia. Critical for its pathogenesis is the ability of the phagocytosed bacteria to escape into the cell cytosol. For this, the bacteria use a non-canonical type VI secretion system (T6SS) encoded on the...

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Detalles Bibliográficos
Autores principales: Brodmann, Maj, Dreier, Roland F., Broz, Petr, Basler, Marek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481754/
https://www.ncbi.nlm.nih.gov/pubmed/28621333
http://dx.doi.org/10.1038/ncomms15853