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Integrative approach in the era of failing drug discovery and development

The productivity decline in drug discovery and development is mainly caused by two factors; higher regulatory hurdles and low-hanging fruits being all picked. In addition, the recent target-based approach is thought to be increasing the price of innovation. Although target-based approach had many su...

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Detalles Bibliográficos
Autores principales: Earm, Keehyun, Earm, Yung E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481768/
https://www.ncbi.nlm.nih.gov/pubmed/28664100
http://dx.doi.org/10.1016/j.imr.2014.09.002