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Structural insights into the function of ZRANB3 in replication stress response

Strategies to resolve replication blocks are critical for the maintenance of genome stability. Among the factors implicated in the replication stress response is the ATP-dependent endonuclease ZRANB3. Here, we present the structure of the ZRANB3 HNH (His-Asn-His) endonuclease domain and provide a de...

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Detalles Bibliográficos
Autores principales: Sebesta, Marek, Cooper, Christopher D. O., Ariza, Antonio, Carnie, Christopher J., Ahel, Dragana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481773/
https://www.ncbi.nlm.nih.gov/pubmed/28621305
http://dx.doi.org/10.1038/ncomms15847