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Glycogen controls Caenorhabditis elegans lifespan and resistance to oxidative stress

A high-sugar diet has been associated with reduced lifespan in organisms ranging from worms to mammals. However, the mechanisms underlying the harmful effects of glucose are poorly understood. Here we establish a causative relationship between endogenous glucose storage in the form of glycogen, resi...

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Detalles Bibliográficos
Autores principales: Gusarov, Ivan, Pani, Bibhusita, Gautier, Laurent, Smolentseva, Olga, Eremina, Svetlana, Shamovsky, Ilya, Katkova-Zhukotskaya, Olga, Mironov, Alexander, Nudler, Evgeny
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481799/
https://www.ncbi.nlm.nih.gov/pubmed/28627510
http://dx.doi.org/10.1038/ncomms15868