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Glycogen controls Caenorhabditis elegans lifespan and resistance to oxidative stress
A high-sugar diet has been associated with reduced lifespan in organisms ranging from worms to mammals. However, the mechanisms underlying the harmful effects of glucose are poorly understood. Here we establish a causative relationship between endogenous glucose storage in the form of glycogen, resi...
Autores principales: | Gusarov, Ivan, Pani, Bibhusita, Gautier, Laurent, Smolentseva, Olga, Eremina, Svetlana, Shamovsky, Ilya, Katkova-Zhukotskaya, Olga, Mironov, Alexander, Nudler, Evgeny |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481799/ https://www.ncbi.nlm.nih.gov/pubmed/28627510 http://dx.doi.org/10.1038/ncomms15868 |
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