Molecular Docking, Molecular Dynamics, and Structure–Activity Relationship Explorations of 14-Oxygenated N-Methylmorphinan-6-ones as Potent μ-Opioid Receptor Agonists

[Image: see text] Among opioids, morphinans are of major importance as the most effective analgesic drugs acting primarily via μ-opioid receptor (μ-OR) activation. Our long-standing efforts in the field of opioid analgesics from the class of morphinans led to N-methylmorphinan-6-ones differently sub...

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Detalles Bibliográficos
Autores principales: Noha, Stefan M., Schmidhammer, Helmut, Spetea, Mariana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481819/
https://www.ncbi.nlm.nih.gov/pubmed/28125215
http://dx.doi.org/10.1021/acschemneuro.6b00460

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481819/
https://www.ncbi.nlm.nih.gov/pubmed/28125215
http://dx.doi.org/10.1021/acschemneuro.6b00460

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