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Lipid-mediated PX-BAR domain recruitment couples local membrane constriction to endocytic vesicle fission

Clathrin-mediated endocytosis (CME) involves membrane-associated scaffolds of the bin-amphiphysin-rvs (BAR) domain protein family as well as the GTPase dynamin, and is accompanied and perhaps triggered by changes in local lipid composition. How protein recruitment, scaffold assembly and membrane def...

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Detalles Bibliográficos
Autores principales: Schöneberg, Johannes, Lehmann, Martin, Ullrich, Alexander, Posor, York, Lo, Wen-Ting, Lichtner, Gregor, Schmoranzer, Jan, Haucke, Volker, Noé, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481832/
https://www.ncbi.nlm.nih.gov/pubmed/28627515
http://dx.doi.org/10.1038/ncomms15873