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Bioengineered constructs combined with exercise enhance stem cell-mediated treatment of volumetric muscle loss

Volumetric muscle loss (VML) is associated with loss of skeletal muscle function, and current treatments show limited efficacy. Here we show that bioconstructs suffused with genetically-labelled muscle stem cells (MuSCs) and other muscle resident cells (MRCs) are effective to treat VML injuries in m...

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Detalles Bibliográficos
Autores principales: Quarta, Marco, Cromie, Melinda, Chacon, Robert, Blonigan, Justin, Garcia, Victor, Akimenko, Igor, Hamer, Mark, Paine, Patrick, Stok, Merel, Shrager, Joseph B., Rando, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481841/
https://www.ncbi.nlm.nih.gov/pubmed/28631758
http://dx.doi.org/10.1038/ncomms15613