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Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130

BACKGROUND: Retinal detachment (RD) can lead to proliferative vitreoretinopathy (PVR), a leading cause of intractable vision loss. PVR is associated with a cytokine storm involving common proinflammatory molecules like IL6, but little is known about the source and downstream signaling of IL6 and the...

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Detalles Bibliográficos
Autores principales: Wang, Xinlei, Miller, Eric B., Goswami, Mayank, Zhang, Pengfei, Ronning, Kaitryn E., Karlen, Sarah J., Zawadzki, Robert J., Pugh, Edward N., Burns, Marie E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481880/
https://www.ncbi.nlm.nih.gov/pubmed/28645275
http://dx.doi.org/10.1186/s12974-017-0886-6