Neonatal AAV delivery of alpha-synuclein induces pathology in the adult mouse brain

Abnormal accumulation of alpha-synuclein (αsyn) is a pathological hallmark of Lewy body related disorders such as Parkinson’s disease and Dementia with Lewy body disease. During the past two decades, a myriad of animal models have been developed to mimic pathological features of synucleinopathies by...

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Detalles Bibliográficos
Autores principales: Delenclos, Marion, Faroqi, Ayman H., Yue, Mei, Kurti, Aishe, Castanedes-Casey, Monica, Rousseau, Linda, Phillips, Virginia, Dickson, Dennis W., Fryer, John D., McLean, Pamela J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481919/
https://www.ncbi.nlm.nih.gov/pubmed/28645308
http://dx.doi.org/10.1186/s40478-017-0455-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481919/
https://www.ncbi.nlm.nih.gov/pubmed/28645308
http://dx.doi.org/10.1186/s40478-017-0455-3

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