Aberrant intestinal microbiota due to IL-1 receptor antagonist deficiency promotes IL-17- and TLR4-dependent arthritis

BACKGROUND: Perturbation of commensal intestinal microbiota has been associated with several autoimmune diseases. Mice deficient in interleukin-1 receptor antagonist (Il1rn (−/−) mice) spontaneously develop autoimmune arthritis and are susceptible to other autoimmune diseases such as psoriasis, diab...

Cur síos iomlán

Sonraí bibleagrafaíochta
Príomhchruthaitheoirí: Rogier, Rebecca, Ederveen, Thomas H. A., Boekhorst, Jos, Wopereis, Harm, Scher, Jose U., Manasson, Julia, Frambach, Sanne J. C. M., Knol, Jan, Garssen, Johan, van der Kraan, Peter M., Koenders, Marije I., van den Berg, Wim B., van Hijum, Sacha A. F. T., Abdollahi-Roodsaz, Shahla
Formáid: Online Alt Téacs
Teanga:English
Foilsithe / Cruthaithe: BioMed Central 2017
Ábhair:
Research
Rochtain ar líne:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481968/
https://www.ncbi.nlm.nih.gov/pubmed/28645307
http://dx.doi.org/10.1186/s40168-017-0278-2

Ar líne

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5481968/
https://www.ncbi.nlm.nih.gov/pubmed/28645307
http://dx.doi.org/10.1186/s40168-017-0278-2

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