Toxic proteins from Croton tiglium L. exert a proinflammatory effect by inducing release of proinflammatory cytokines and activating the p38-MAPK signaling pathway

The aim of the present study was to determine the toxic targets of proteins from Croton tiglium L. and to investigate the potential mechanism of their toxicity. The toxic targets were determined by oral medication and intraperitoneal injection. The median lethal dose of oral medication in mice was c...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Liping, Yu, Hongli, Wu, Hao, Yang, Xiaolin, Pan, Yaozong, Chen, Yeqing, Wang, Kuilong, Wang, Wei, Zhang, Wenying, Jin, Yangping, Zhang, Chengchao, Jiang, Ai, Xia, Chunyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482117/
https://www.ncbi.nlm.nih.gov/pubmed/28560398
http://dx.doi.org/10.3892/mmr.2017.6617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482117/
https://www.ncbi.nlm.nih.gov/pubmed/28560398
http://dx.doi.org/10.3892/mmr.2017.6617

Ejemplares similares