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Toxic proteins from Croton tiglium L. exert a proinflammatory effect by inducing release of proinflammatory cytokines and activating the p38-MAPK signaling pathway
The aim of the present study was to determine the toxic targets of proteins from Croton tiglium L. and to investigate the potential mechanism of their toxicity. The toxic targets were determined by oral medication and intraperitoneal injection. The median lethal dose of oral medication in mice was c...
Autores principales: | Liu, Liping, Yu, Hongli, Wu, Hao, Yang, Xiaolin, Pan, Yaozong, Chen, Yeqing, Wang, Kuilong, Wang, Wei, Zhang, Wenying, Jin, Yangping, Zhang, Chengchao, Jiang, Ai, Xia, Chunyan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482117/ https://www.ncbi.nlm.nih.gov/pubmed/28560398 http://dx.doi.org/10.3892/mmr.2017.6617 |
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