Enhanced effect of nuclear localization signal peptide during ultrasound-targeted microbubble destruction-mediated gene transfection

Ultrasound-targeted microbubble destruction (UTMD) can promote the entry of plasmid DNA (pDNA) into the cell cytoplasm, by increasing the permeability of the cell membrane. But the transfection efficiency remains low due to inability of the pDNA to enter the nucleus. Various methods have been explor...

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Detalles Bibliográficos
Autores principales: Cao, Sheng, Zhou, Qing, Chen, Jin-Ling, Jiang, Nan, Wang, Yi-Jia, Deng, Qing, Hu, Bo, Guo, Rui-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482142/
https://www.ncbi.nlm.nih.gov/pubmed/28586046
http://dx.doi.org/10.3892/mmr.2017.6661

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482142/
https://www.ncbi.nlm.nih.gov/pubmed/28586046
http://dx.doi.org/10.3892/mmr.2017.6661

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