Cargando…

Metformin ameliorates hepatic steatosis and improves the induction of autophagy in HFD-induced obese mice

The present study aimed to investigate the effect of metformin on the induction of autophagy in the liver and adipose tissues of a mouse model of obesity. C57BL/6J mice were fed a high-fat diet (HFD) for 12 weeks to induce obesity-associated hepatic steatosis, and treated with metformin (150 mg/kg/d...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Min, Sharma, Antara, Yin, Chunyan, Tan, Xinrui, Xiao, Yanfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482143/
https://www.ncbi.nlm.nih.gov/pubmed/28560428
http://dx.doi.org/10.3892/mmr.2017.6637