Cargando…
Metformin ameliorates hepatic steatosis and improves the induction of autophagy in HFD-induced obese mice
The present study aimed to investigate the effect of metformin on the induction of autophagy in the liver and adipose tissues of a mouse model of obesity. C57BL/6J mice were fed a high-fat diet (HFD) for 12 weeks to induce obesity-associated hepatic steatosis, and treated with metformin (150 mg/kg/d...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482143/ https://www.ncbi.nlm.nih.gov/pubmed/28560428 http://dx.doi.org/10.3892/mmr.2017.6637 |