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Metformin ameliorates hepatic steatosis and improves the induction of autophagy in HFD-induced obese mice

The present study aimed to investigate the effect of metformin on the induction of autophagy in the liver and adipose tissues of a mouse model of obesity. C57BL/6J mice were fed a high-fat diet (HFD) for 12 weeks to induce obesity-associated hepatic steatosis, and treated with metformin (150 mg/kg/d...

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Detalles Bibliográficos
Autores principales:	Li, Min, Sharma, Antara, Yin, Chunyan, Tan, Xinrui, Xiao, Yanfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2017
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482143/ https://www.ncbi.nlm.nih.gov/pubmed/28560428 http://dx.doi.org/10.3892/mmr.2017.6637

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