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Inhibition of IGF-1 receptor kinase blocks the differentiation into cardiomyocyte-like cells of BMSCs induced by IGF-1

Bone marrow mesenchymal stem cells (BMSCs) have the potential to transdifferentiate into cardiomyocyte-like cells (CLCs) if an appropriate cardiac environment is provided. Insulin-like growth factor-1 (IGF-1) plays an important role in the cell migration, survival and differentiation of BMSCs. Howev...

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Detalles Bibliográficos
Autores principales: Gong, Haibin, Wang, Xiuli, Wang, Lei, Liu, Ying, Wang, Jie, Lv, Qian, Pang, Hui, Zhang, Qinglin, Wang, Zhenquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482190/
https://www.ncbi.nlm.nih.gov/pubmed/28560388
http://dx.doi.org/10.3892/mmr.2017.6639