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Inhibition of IGF-1 receptor kinase blocks the differentiation into cardiomyocyte-like cells of BMSCs induced by IGF-1
Bone marrow mesenchymal stem cells (BMSCs) have the potential to transdifferentiate into cardiomyocyte-like cells (CLCs) if an appropriate cardiac environment is provided. Insulin-like growth factor-1 (IGF-1) plays an important role in the cell migration, survival and differentiation of BMSCs. Howev...
Autores principales: | Gong, Haibin, Wang, Xiuli, Wang, Lei, Liu, Ying, Wang, Jie, Lv, Qian, Pang, Hui, Zhang, Qinglin, Wang, Zhenquan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482190/ https://www.ncbi.nlm.nih.gov/pubmed/28560388 http://dx.doi.org/10.3892/mmr.2017.6639 |
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