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Computational approaches for de novo design and redesign of metal-binding sites on proteins

Metal ions play pivotal roles in protein structure, function and stability. The functional and structural diversity of proteins in nature expanded with the incorporation of metal ions or clusters in proteins. Approximately one-third of these proteins in the databases contain metal ions. Many biologi...

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Detalles Bibliográficos
Autores principales: Akcapinar, Gunseli Bayram, Sezerman, Osman Ugur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482196/
https://www.ncbi.nlm.nih.gov/pubmed/28167677
http://dx.doi.org/10.1042/BSR20160179