Identification of Novel G Protein–Coupled Receptor 143 Ligands as Pharmacologic Tools for Investigating X-Linked Ocular Albinism

PURPOSE: GPR143 regulates melanosome biogenesis and organelle size in pigment cells. The mechanisms underlying receptor function remain unclear. G protein–coupled receptors (GPCRs) are excellent pharmacologic targets; thus, we developed and applied a screening approach to identify potential GPR143 l...

Descripción completa

Detalles Bibliográficos
Autores principales: De Filippo, Elisabetta, Manga, Prashiela, Schiedel, Anke C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2017
Materias:
Biochemistry and Molecular Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482243/
https://www.ncbi.nlm.nih.gov/pubmed/28632878
http://dx.doi.org/10.1167/iovs.16-21128

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482243/
https://www.ncbi.nlm.nih.gov/pubmed/28632878
http://dx.doi.org/10.1167/iovs.16-21128

Ejemplares similares