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Segregation Lag in Polyploid Cells of the Pathogen Genus Borrelia: Implications for Antigenic Variation


Relapsing fever agents like Borrelia hermsii undergo multiphasic antigenic variation that is attributable to spontaneous DNA non-reciprocal transpositions at a particular locus in the genome. This genetic switch results in a new protein being expressed on the cell surface, allowing cells with that p...

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Detalles Bibliográficos
Autores principales: Crowder, Christopher D., Denny, Richard L., Barbour, Alan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482298/
https://www.ncbi.nlm.nih.gov/pubmed/28656008