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BiP: Master Regulator of the Unfolded Protein Response and Crucial Factor in Flavivirus Biology


Flaviviruses have an intimate relationship with their host cells, utilizing host proteins during replication. Much of viral genome replication and virion assembly occurs on and within the endoplasmic reticulum (ER). As a cellular protein folding hub, the ER provides an ideal environment for flavivir...

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Detalles Bibliográficos
Autores principales: Lewy, Tyler G., Grabowski, Jeffrey M., Bloom, Marshall E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: YJBM 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482305/
https://www.ncbi.nlm.nih.gov/pubmed/28656015