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Recent advances in high-throughput approaches to dissect enhancer function

The regulation of gene transcription in higher eukaryotes is accomplished through the involvement of transcription start site (TSS)-proximal (promoters) and -distal (enhancers) regulatory elements. It is now well acknowledged that enhancer elements play an essential role during development and cell...

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Detalles Bibliográficos
Autores principales: Santiago-Algarra, David, Dao, Lan T.M., Pradel, Lydie, España, Alexandre, Spicuglia, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482341/
https://www.ncbi.nlm.nih.gov/pubmed/28690838
http://dx.doi.org/10.12688/f1000research.11581.1