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A simple mathematical approach to the analysis of polypharmacology and polyspecificity data

There many possible types of drug-target interactions, because there are a surprising number of ways in which drugs and their targets can associate with one another.  These relationships are expressed as polypharmacology and polyspecificity.  Polypharmacology is the capability of a given drug to exh...

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Detalles Bibliográficos
Autores principales: Maggiora, Gerry, Gokhale, Vijay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482344/
https://www.ncbi.nlm.nih.gov/pubmed/28690829
http://dx.doi.org/10.12688/f1000research.11517.1