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Sirt6 alters adult hippocampal neurogenesis
Sirtuins are pleiotropic NAD(+) dependent histone deacetylases involved in metabolism, DNA damage repair, inflammation and stress resistance. SIRT6, a member of the sirtuin family, regulates the process of normal aging and increases the lifespan of male mice over-expressing Sirt6 by 15%. Neurogenesi...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482455/ https://www.ncbi.nlm.nih.gov/pubmed/28644902 http://dx.doi.org/10.1371/journal.pone.0179681 |