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Sirt6 alters adult hippocampal neurogenesis

Sirtuins are pleiotropic NAD(+) dependent histone deacetylases involved in metabolism, DNA damage repair, inflammation and stress resistance. SIRT6, a member of the sirtuin family, regulates the process of normal aging and increases the lifespan of male mice over-expressing Sirt6 by 15%. Neurogenesi...

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Detalles Bibliográficos
Autores principales:	Okun, Eitan, Marton, Daniel, Cohen, Daniel, Griffioen, Kathleen, Kanfi, Yariv, Illouz, Tomer, Madar, Ravit, Cohen, Haim Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2017
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482455/ https://www.ncbi.nlm.nih.gov/pubmed/28644902 http://dx.doi.org/10.1371/journal.pone.0179681

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