O-GlcNAcylation mediates the control of cytosolic phosphoenolpyruvate carboxykinase activity via Pgc1α

PGC1α is a coactivator of many transcription factors and cytosolic phosphoenolpyruvate carboxykinase (PCK1) is a key enzyme for gluconeogenesis. PGC1α interacts with the transcription factor PPARγ to stimulate PCK1 expression and thus de novo glucose synthesis. These proteins are not only important...

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Detalles Bibliográficos
Autores principales: Latorre, Pedro, Varona, Luis, Burgos, Carmen, Carrodeguas, José A., López-Buesa, Pascual
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482481/
https://www.ncbi.nlm.nih.gov/pubmed/28644880
http://dx.doi.org/10.1371/journal.pone.0179988

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482481/
https://www.ncbi.nlm.nih.gov/pubmed/28644880
http://dx.doi.org/10.1371/journal.pone.0179988

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