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Metabolic network segmentation: A probabilistic graphical modeling approach to identify the sites and sequential order of metabolic regulation from non-targeted metabolomics data

In recent years, the number of large-scale metabolomics studies on various cellular processes in different organisms has increased drastically. However, it remains a major challenge to perform a systematic identification of mechanistic regulatory events that mediate the observed changes in metabolit...

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Detalles Bibliográficos
Autores principales: Kuehne, Andreas, Mayr, Urs, Sévin, Daniel C., Claassen, Manfred, Zamboni, Nicola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482507/
https://www.ncbi.nlm.nih.gov/pubmed/28598965
http://dx.doi.org/10.1371/journal.pcbi.1005577