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Metabolic network segmentation: A probabilistic graphical modeling approach to identify the sites and sequential order of metabolic regulation from non-targeted metabolomics data
In recent years, the number of large-scale metabolomics studies on various cellular processes in different organisms has increased drastically. However, it remains a major challenge to perform a systematic identification of mechanistic regulatory events that mediate the observed changes in metabolit...
Autores principales: | Kuehne, Andreas, Mayr, Urs, Sévin, Daniel C., Claassen, Manfred, Zamboni, Nicola |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482507/ https://www.ncbi.nlm.nih.gov/pubmed/28598965 http://dx.doi.org/10.1371/journal.pcbi.1005577 |
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