Saxifragifolin D attenuates phagosome maturation arrest in Mycobacterium tuberculosis-infected macrophages via an AMPK and VPS34-dependent pathway

Saxifragifolin D (SD), a traditional Chinese medicine, is a pentacyclic triterpenoid compound first isolated from Androsace umbellata. Various plant triterpenoids have been reported to exhibit antitubercular activity. In this study, THP-1-derived macrophages were infected with an attenuated M. tuber...

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Detalles Bibliográficos
Autores principales: Zhou, Jia, Xu, Rui, Du, Xian-zhi, Zhou, Xiang-dong, Li, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482509/
https://www.ncbi.nlm.nih.gov/pubmed/28050854
http://dx.doi.org/10.1186/s13568-016-0317-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482509/
https://www.ncbi.nlm.nih.gov/pubmed/28050854
http://dx.doi.org/10.1186/s13568-016-0317-6

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