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The Anopheles gambiae 2La chromosome inversion is associated with susceptibility to Plasmodium falciparum in Africa

Chromosome inversions suppress genetic recombination and establish co-adapted gene complexes, or supergenes. The 2La inversion is a widespread polymorphism in the Anopheles gambiae species complex, the major African mosquito vectors of human malaria. Here we show that alleles of the 2La inversion ar...

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Detalles Bibliográficos
Autores principales: Riehle, Michelle M, Bukhari, Tullu, Gneme, Awa, Guelbeogo, Wamdaogo M, Coulibaly, Boubacar, Fofana, Abdrahamane, Pain, Adrien, Bischoff, Emmanuel, Renaud, Francois, Beavogui, Abdoul H, Traore, Sekou F, Sagnon, N’Fale, Vernick, Kenneth D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5482571/
https://www.ncbi.nlm.nih.gov/pubmed/28643631
http://dx.doi.org/10.7554/eLife.25813